Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy
Identifieur interne : 003869 ( Main/Exploration ); précédent : 003868; suivant : 003870Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy
Auteurs : Jan Lewerenz [Allemagne] ; Bartosz Zurowski [Allemagne] ; Lars Jenicke [Allemagne] ; Tobias B Umer [Allemagne] ; Andrew Lees (neurologue) [Royaume-Uni] ; Alexander Münchau [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-08.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Déficit.
English descriptors
- KwdEn :
- Adult, Corpus Striatum (metabolism), Corpus Striatum (pathology), Corpus Striatum (radionuclide imaging), Deficiency, Dopamine, Dopamine (metabolism), Humans, Magnetic Resonance Imaging (methods), Male, Mesencephalon (injuries), Mesencephalon (pathology), Mesencephalon (radionuclide imaging), Midbrain, Mimic, Nervous system diseases, Neurosurgery (methods), PSP, Pinealoma (surgery), Postoperative Complications, Substantia Nigra (metabolism), Substantia Nigra (pathology), Substantia Nigra (radionuclide imaging), Supranuclear Palsy, Progressive (etiology), Supranuclear Palsy, Progressive (physiopathology), Supranuclear Palsy, Progressive (radionuclide imaging), Tomography, Emission-Computed, Single-Photon (methods), axial rigidity, dopamine deficiency, dorsorostral midbrain lesion.
- MESH :
- chemical , metabolism : Dopamine.
- etiology : Supranuclear Palsy, Progressive.
- injuries : Mesencephalon.
- metabolism : Corpus Striatum, Substantia Nigra.
- methods : Magnetic Resonance Imaging, Neurosurgery, Tomography, Emission-Computed, Single-Photon.
- pathology : Corpus Striatum, Mesencephalon, Substantia Nigra.
- physiopathology : Supranuclear Palsy, Progressive.
- radionuclide imaging : Corpus Striatum, Mesencephalon, Substantia Nigra, Supranuclear Palsy, Progressive.
- surgery : Pinealoma.
- Adult, Humans, Male, Postoperative Complications.
Abstract
We report on a patient with a residual dorsorostral midbrain lesion after resection of a pineal gland tumor. In addition to severe vertical gaze palsy, this patient exhibited other neurological features closely resembling progressive supranuclear palsy. Normal dopamine transporter single‐photon emission computed tomography imaging excluded significant dopamine deficiency. We suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20484
Affiliations:
- Allemagne, Royaume-Uni
- Angleterre, Grand Londres, Hambourg
- Hambourg, Londres
- National Hospital for Neurology and Neurosurgery
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In addition to severe vertical gaze palsy, this patient exhibited other neurological features closely resembling progressive supranuclear palsy. Normal dopamine transporter single‐photon emission computed tomography imaging excluded significant dopamine deficiency. We suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension. © 2005 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li><li>Hambourg</li></region><settlement><li>Hambourg</li><li>Londres</li></settlement><orgName><li>National Hospital for Neurology and Neurosurgery</li></orgName></list><tree><country name="Allemagne"><region name="Hambourg"><name sortKey="Lewerenz, Jan" sort="Lewerenz, Jan" uniqKey="Lewerenz J" first="Jan" last="Lewerenz">Jan Lewerenz</name></region><name sortKey="B Umer, Tobias" sort="B Umer, Tobias" uniqKey="B Umer T" first="Tobias" last="B Umer">Tobias B Umer</name><name sortKey="Jenicke, Lars" sort="Jenicke, Lars" uniqKey="Jenicke L" first="Lars" last="Jenicke">Lars Jenicke</name><name sortKey="Munchau, Alexander" sort="Munchau, Alexander" uniqKey="Munchau A" first="Alexander" last="Münchau">Alexander Münchau</name><name sortKey="Zurowski, Bartosz" sort="Zurowski, Bartosz" uniqKey="Zurowski B" first="Bartosz" last="Zurowski">Bartosz Zurowski</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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